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You are required to write a report (around 1200 to 1,500 words) using a case study approach describing the pathophysiology, specific biochemical profile characteristics observed that led to the provisional diagnosis

Assessment details:

  1. Template to be used to write the report (with some tips to help you prepare the report)
  2. Marking guide which will be used in the assessment process(with some tips to help you prepare the report)

You are required to write a report (around 1200 to 1,500 words) using a case study approach describing the pathophysiology, specific biochemical profile characteristics observed that led to the provisional diagnosis, differential diagnoses and potential treatment options. You may also recommended further tests that will assist in confirming the diagnosis. Further details on the case, a template and an exemplar will be provided to you on the Moodle site to assist in preparation.

The submitted assessment items must be your own work, and not written, prepared, or composed using Generative AI tools (GenAI/LLM). This includes the manipulation or analysis of images and data.Note: Cutting and pasting of GenAI/LLM material into assessments may be considered contract cheating and/or plagiarism.

Case study1

A59-year-oldmale,Mr.JonesRobert,wasadmittedtotheICUwithaleakingaortic aneurysm. His BP was 110/60 mmHg and pulse rate 107 bpm.

A pre-operative assessment performed 5 days prior revealed normal serum U&Eresults, specifically Urea 5.3 mmol/L and Creatinine 0.09 mmol/L.

TherequestformandhistestresultsonadmissiontoICUareshownbelow.

BUCKETPATHOLOGYREQUESTFORM

Surname

Robert

GivenName

Jones

Dateofbirth

18.01.1965

URNumber

9853

Gender

M

Ward

ICU

Historyand medication

Post-operativeleakingaorticaneurysmrepair

Testsrequested

FASTING

RANDOM

Blood-UEC,Osmolality

RequestingDrs Name

Dr.SimonPhilip

Requesting Drssignature

Simon

CollectionDeclaration:Icertifythatthebloodspecimen(s)accompanyingthisrequestwasdrawnfromthe patient named above and I established the identity of this patient by direct inquiry and/or by inspection of wristband and immediately upon the blood being drawn I labelled the specimen(s).

CollectionDate 14.02.2025

Time 07.40

Signed:MaryCain

SerumBiochemistry:

Analyte

Patientresults

Referenceranges

Sodium

147

132144mmol/L

Potassium

4.3

3.24.8mmol/L

Chloride

105

98108mmol/L

Bicarbonate

30

2333mmol/L

Aniongap

16

1017mmol/L

Urea

20.4

3.08.0mmol/L

Creatinine

0.21

0.060.12mmol/L

Osmolality

320

275295mosmol/kg

The patient was transfused with several units of blood which stabilised his BP. A urine sample was then collected and the electrolytes analysed

UrineBiochemistry:

Urea

380mmol/L

Creatinine

6.5mmol/L

Sodium

49mmol/L

Chloride

19mmol/L

Osmolality

504mosmol/kg

Write a report (approximately 1,500 words) on what you think Jones’s condition/s might be.
Consider the results in relation to one another and suggest further tests that may help in confirming or eliminating differential diagnoses.
Please make sure you use the case report template to write your report. This template also outlines a series of tips to help you structure the report and areas to focus your report on.
A detailed marking rubric & guide has also been provided to you to help you in writing the report.

Tips:

The total word count for this case study report is between 1200 to 1500

words (excluding references).

Reports should be typed in Word and adhere to the format of the given

template (Arial, 12pt, Single spacing).

The report must include your name and page

numbers should be included in the footer of all pages of the report.

“Be sure to carefully review the rubric for detailed criteria and the

breakdown of marks.”

Total marks: 100 marks

Total weighting of this assessment: 20%

Additional Tips

  1. The report should be written in scientific style. Use the correctterminology where appropriate.
  2. Avoid using ownership words or starting sentencing with I, we, me,they, you, e.g. dont write I think that.., then I and so on. Instead use statements such as, the results suggest..
  3. When you are finished, ask someone else to proofread your report and let you know if they understand what you have written. They may give you some suggestions about the clarity and spot some typos you have overlooked! Your practical report should clearly explain the clinical history and reason for testing, as well as, what tests you have performed, why you did those, the results that you obtained, and an explanation of their significance.

Please DO NOT submit a PDF version of your draft assessment on the

You are required to write a report (around 1200 to 1,500 words) using a case study approach describing the pathophysiology, specific biochemical profile characteristics observed that led to the provisional diagnosis
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